lumi **

Lumi is an ongoing project for Illumina microarray data analysis, including the design of a software package in R/Bioconductor and the discussion of microarray experiment design.

** an open source project at the Bioinformatics Core of the Robert H. Lurie Comprehensive Cancer Center, Northwestern University.


No Panacea (yet): NGS for Small RNA

"NGS is the future", so it was said. However, the NGS-based digital expression profiling of small RNA is reported to be biased. The problem appears not to be the NGS platforms (SOLiD or Solexa), but the methods used for preparing the small RNA library.

Here is the link to the Nature Methods (July 2009) paper

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